Lamellar ichthyosis–like eruption associated with ponatinib

Pulmonary hypertension associated with ponatinib therapy.

Over 50 drugs, including anorexigens, abused substances and recently the tyrosine kinase inhibitor (TKI) dasatinib, have been temporally and/or mechanistically related to the development of pulmonary arterial hypertension (PAH) in humans (where the evidence base for causality is wide ranging) and in animal models [1–3]. The TKIs imatinib, dasatinib, nilotinib and bosutinib are available to trea...

Fixed drug eruption associated with anaesthesia.

We report the case of a 65-yr-old woman undergoing bronchoscopy for a lobular lesion who received thiopentone to induce anaesthesia that was maintained with sufentanil, vecuronium and isoflurane. She tolerated the procedure well initially, but developed eruptions about her face and fingers within 24 hr of anaesthesia. Treatment with flucinonide cream (0.05%) resolved the eruptions with no lasti...

Psoriasiform skin eruption associated with sorafenib therapy.

Inverse lichenoid drug eruption associated with nivolumab

PD-1: programmed cell death protein

Bullous skin eruption associated with carbamazepine overdosage.

A patient who developed a bullous skin eruption associated with carbamazepine overdosage is described. The authors believe this previously unreported phenomenon to be of clinical importance. Carbamazepine should be considered in the differential diagnosis of drug-induced coma with associated bullous lesions.